STARTING OHYTUVAYRE

Support for getting your medication

Once you have been prescribed OHTUVAYRE, the next step is getting your medication — and we are here to help.


Call to get started with enrollment

1-833-372-8492
Available Monday through Friday,
8 AM to 8 PM ET

Next steps for getting your medication:

Your doctor’s office will send in your prescription information.

You will receive a welcome call to help you identify your insurance coverage and, if needed, explore financial assistance options.a

Once approved, your Specialty Pharmacy will call to arrange how you will receive OHTUVAYRE and any supplies you may need.

aYou must be enrolled in The Merck Access Program to receive financial assistance information.

Questions about paying for OHTUVAYRE?

A Merck Access Program representative
can provide information about:

Co-pay Coupon Program*

Eligible, privately insured patients may save on their out-of-pocket costs for their prescriptions for OHTUVAYRE. Not valid for patients who are uninsured or patients with Medicare or other Government Program insurance.

Not all patients are eligible. Certain restrictions apply.

Please see Terms and Conditions.

The Merck Access Program

If you have questions about accessing OHTUVAYRE, understanding your insurance coverage, or working with your Specialty Pharmacy, support is available.

*Contact The Merck Access Program at 1-833-372-8492
Mon-Fri, 8 AM to 8 PM ET, to speak to a representative.

Learn more about The Merck Access Program

A Specialty Pharmacy fills OHTUVAYRE prescriptions. They will call you to arrange how you will receive OHTUVAYRE and any supplies you may need.

The Specialty Pharmacy will:

  • Provide you information about your OHTUVAYRE prescription and next steps in the process
  • Give you 24/7 access to a Clinical Pharmacist to help with questions
  • Provide reminders and ways to schedule refills

Indication

OHTUVAYRE® (ensifentrine) is a prescription medicine used to treat chronic obstructive pulmonary disease (COPD) in adults. COPD is a chronic (long-term) lung disease that includes chronic bronchitis, emphysema, or both.

Select Safety Information

What is the most important information I should know about OHTUVAYRE?

OHTUVAYRE can cause serious side effects, including:

  • Sudden breathing problems immediately after inhaling your medicine. If you have sudden breathing problems immediately after inhaling your medicine, stop using OHTUVAYRE and call your healthcare provider right away or go to the nearest hospital emergency room right away.
  • Mental health problems including suicidal thoughts and behavior. You may experience mood or behavior changes when taking OHTUVAYRE. Call your healthcare provider right away if you have any of these symptoms, especially if they are new, worse, or worry you: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety, new or worse depression, acting on dangerous impulses, and/or other unusual changes in your behavior or mood.

Do not use OHTUVAYRE to treat sudden breathing problems. Always have a rescue inhaler with you.

 

Who should not use OHTUVAYRE?

 

Do not use OHTUVAYRE if you have had an allergic reaction to ensifentrine or any of the ingredients in OHTUVAYRE.

 

What should I tell my healthcare provider before using OHTUVAYRE?

 

Before you use OHTUVAYRE, tell your healthcare provider if you have or have had a history of mental health problems including depression and suicidal behavior; have liver problems; are pregnant or plan to become pregnant; or are breastfeeding. It is not known if OHTUVAYRE may harm your unborn baby. It is not known if the medicine in OHTUVAYRE passes into your breast milk and if it can harm your baby.

 

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

 

What are the most common side effects of OHTUVAYRE?

 

The most common side effects of OHTUVAYRE include back pain, high blood pressure, bladder infection, and diarrhea.

 

These are not all the possible side effects of OHTUVAYRE. Call your doctor for medical advice about side effects.

 

How should I use OHTUVAYRE?

  • OHTUVAYRE is only for use with a nebulizer.
  • Do not use OHTUVAYRE unless your healthcare provider has taught you how to use it with your nebulizer and you understand how to use it correctly.
  • Use OHTUVAYRE exactly as your healthcare provider tells you to use it. Do not use OHTUVAYRE more often than prescribed.
  • OHTUVAYRE is taken as a breathing treatment by oral (mouth) inhalation and should be used with a standard jet nebulizer with a mouthpiece connected to an air compressor.
  • Do not mix other medicines with OHTUVAYRE in your nebulizer.

 

This summary does not include all the information about OHTUVAYRE and is not meant to take the place of a discussion with your healthcare provider about your treatment. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

 

Please read the accompanying Patient Information and Instructions for Use for OHTUVAYRE, and discuss them with your doctor. The physician Prescribing Information also is available.

 

INDICATION
SELECT SAFETY INFORMATION

OHTUVAYRE® (ensifentrine) is a prescription medicine used to treat chronic obstructive pulmonary disease (COPD) in adults. COPD is a chronic (long-term) lung disease that includes chronic bronchitis, emphysema, or both.

SELECT SAFETY INFORMATION

What is the most important information I should know about OHTUVAYRE?

OHTUVAYRE can cause serious side effects, including:

  • Sudden breathing problems immediately after inhaling your medicine. If you have sudden breathing problems immediately after inhaling your medicine, stop using OHTUVAYRE and call your healthcare provider right away or go to the nearest hospital emergency room right away.
  • Mental health problems including suicidal thoughts and behavior. You may experience mood or behavior changes when taking OHTUVAYRE. Call your healthcare provider right away if you have any of these symptoms, especially if they are new, worse, or worry you: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety, new or worse depression, acting on dangerous impulses, and/or other unusual changes in your behavior or mood.

Do not use OHTUVAYRE to treat sudden breathing problems. Always have a rescue inhaler with you.

 

Who should not use OHTUVAYRE?

 

Do not use OHTUVAYRE if you have had an allergic reaction to ensifentrine or any of the ingredients in OHTUVAYRE.

 

What should I tell my healthcare provider before using OHTUVAYRE?

 

Before you use OHTUVAYRE, tell your healthcare provider if you have or have had a history of mental health problems including depression and suicidal behavior; have liver problems; are pregnant or plan to become pregnant; or are breastfeeding. It is not known if OHTUVAYRE may harm your unborn baby. It is not known if the medicine in OHTUVAYRE passes into your breast milk and if it can harm your baby.

 

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

 

What are the most common side effects of OHTUVAYRE?

 

The most common side effects of OHTUVAYRE include back pain, high blood pressure, bladder infection, and diarrhea.

 

These are not all the possible side effects of OHTUVAYRE. Call your doctor for medical advice about side effects.

 

How should I use OHTUVAYRE?

  • OHTUVAYRE is only for use with a nebulizer.
  • Do not use OHTUVAYRE unless your healthcare provider has taught you how to use it with your nebulizer and you understand how to use it correctly.
  • Use OHTUVAYRE exactly as your healthcare provider tells you to use it. Do not use OHTUVAYRE more often than prescribed.
  • OHTUVAYRE is taken as a breathing treatment by oral (mouth) inhalation and should be used with a standard jet nebulizer with a mouthpiece connected to an air compressor.
  • Do not mix other medicines with OHTUVAYRE in your nebulizer.

 

This summary does not include all the information about OHTUVAYRE and is not meant to take the place of a discussion with your healthcare provider about your treatment. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

 

Please read the accompanying Patient Information and Instructions for Use for OHTUVAYRE, and discuss them with your doctor. The physician Prescribing Information also is available.